Remnant cholesterol as a new lipid-lowering target to reduce cardiovascular events
P Raggi, ML Becciu, EP Navarese - Current Opinion in Lipidology, 2024 - journals.lww.com
P Raggi, ML Becciu, EP Navarese
Current Opinion in Lipidology, 2024•journals.lww.com… This review aims to summarize the pathophysiological mechanisms, and the current
evidence base from epidemiological investigations and genetic studies that support a
causal link between remnant cholesterol and atherosclerotic cardiovascular disease.
Current and novel therapeutic approaches to target remnant cholesterol are discussed. …
This large MR study showed a robust, genetic, causal association between remnant
cholesterol and atherosclerotic cardiovascular disease outcomes, and it suggested that a …
evidence base from epidemiological investigations and genetic studies that support a
causal link between remnant cholesterol and atherosclerotic cardiovascular disease.
Current and novel therapeutic approaches to target remnant cholesterol are discussed. …
This large MR study showed a robust, genetic, causal association between remnant
cholesterol and atherosclerotic cardiovascular disease outcomes, and it suggested that a …
Summary
In this light, the emerging role of remnant cholesterol as an independent lipid risk marker warrants a reevaluation of lipid management guidelines and underscores the potential for novel therapeutic targets in cardiovascular disease prevention.
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